NanoSPLASH will use an enzymatic chain reaction to ensure that you get a clear diagnosis in less than an hour. Red will indicate an infection and a lack of color will indicate that you are healthy. To ensure rapid results, our design takes advantage of several highly efficient enzyme molecules which evolved in bacteria. As part of the core of the nanoSPLASH platform, we also will utilize single-stranded DNA nanotechnology, further speeding up nanoSPLASH's diagnostic capabilities.
Using DNA-based nanotechnology, nanoSPLASH will recognize the genetic material of the target virus. When this happens, it will initiate the enzymatic chain reaction, leading to the production of a red pigment. Since nanoSPLASH will use a unique sequence of DNA letters to detect the target virus, we anticipate that it will likely exceed the accuracy of antigen-based tests. NanoSPLASH will be the first to unite highly precise molecular recognition with suitability for home use.
NanoSPLASH will employ a unique cocktail of nanobiotechnologies so as to accurately detect the coronavirus and other infectious diseases. Each component of nanoSPLASH has been individually validated by usage in molecular biology laboratories across the world. By bringing together these components in a novel fashion, the device will gain the ability to detect a very small amount of genetic material from the target virus with a high degree of accuracy.